The entertainment world is mourning the loss of a true television legend. Leslie Charleson, best known for her iconic role as Monica Quartermaine on General Hospital, has passed away peacefully at the age of 79. Her death was announced by a colleague through a heartfelt post on social media, triggering an outpouring of love and remembrance from fans and peers alike.
Charleson’s presence on General Hospital spanned nearly five decades—an extraordinary run that made her a household name among soap opera fans. According to Variety, the actress died after a long illness. Though her passing marks the end of an era, the impact she made on daytime television will endure for generations.

Honoring a Legacy of Dedication
General Hospital paid tribute to Charleson through a moving message on its official Instagram page. Executive Producer Frank Valentini described her as the “beloved matriarch” of the series and acknowledged her nearly 50 years of unwavering dedication.
In a personal reflection, Valentini shared, “I’ll deeply miss our daily conversations, her sharp wit, and her vibrant presence on set.” His statement echoed the sentiments of countless others who had the privilege of working alongside her. The team’s collective grief is a testament to just how much Charleson meant to the show and those behind it.
Television executive Nathan Varni also took to X (formerly Twitter) to share his tribute. He highlighted her warmth, her talent, and the simple joy of her company. “The world will forever miss you, Leslie. ,” he wrote, capturing the affection so many felt for her.
A Lifelong Commitment to Her Craft
Born on February 22, 1945, in Kansas City, Missouri, Charleson built a long and respected career in television. Her journey with General Hospital began in 1977, and from the start, she made Monica Quartermaine a central figure in the show’s storied history. She also brought the character to life in spinoffs such as Port Charles and General Hospital: Night Shift.
In a 2019 interview with Digital Journal, Charleson revealed what kept her so deeply connected to the role. “Interest in the material and the relationships formed over the years are why I stayed. Unlike most others, I haven’t hopped from one soap opera to another,” she explained. That sense of loyalty and passion defined her approach and made her a consistent and reliable force in the genre.
More Than Monica: A Versatile Performer

Though her role on General Hospital defined much of her public identity, Charleson was far from a one-dimensional performer. Her career extended into primetime television and film. She made a guest appearance on Friends, acting alongside stars like Jennifer Aniston and Courteney Cox. Her film work included TV movies such as Woman on the Ledge and short films like The Return of the Musketeers.
What stood out to me about Charleson was her ability to adapt to new roles while maintaining a grounded, authentic presence. Whether she was helping to introduce new characters into the Quartermaine family or stepping into entirely different genres, she brought a rare sincerity and grace to every performance.
A Lasting Presence in Television History
Leslie Charleson’s passing is more than the loss of a talented actress—it is the departure of a beloved figure who shaped the landscape of daytime television. Her legacy will live on in the countless storylines she helped shape, the colleagues she mentored, and the viewers she touched with her genuine portrayal of Monica Quartermaine.
As we remember her today, we honor not only her work but the warmth, humor, and heart she brought to it. Leslie Charleson was a remarkable actress and an even more remarkable human being. If her performances meant something to you, or if her presence brightened your afternoons, feel free to share your memories. It’s through those stories that her legacy will continue to live.